[1]雷巧灵,陈 旭,刘文频.温阳复脉益心加减方联合铜砭刮痧治疗老年冠心病并发心律失常疗效研究[J].陕西中医,2024,(3):335-339.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.010]
　LEI Qiaoling,CHEN Xu,LIU Wenpin.Curative effect study on Wenyang Fumai Yixin Jiajian prescription combined with Tongbian Guasha on coronary heart disease accompanied by arrhythmia[J].,2024,(3):335-339.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.010]
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温阳复脉益心加减方联合铜砭刮痧治疗老年冠心病并发心律失常疗效研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年3期
页码:
335-339
栏目:
临床研究
出版日期:
2024-03-05

文章信息/Info

Title:
Curative effect study on Wenyang Fumai Yixin Jiajian prescription combined with Tongbian Guasha on coronary heart disease accompanied by arrhythmia
作者:
雷巧灵; 陈 旭; 刘文频
(湖南中医药大学第二附属医院,湖南 长沙 410005)
Author(s):
LEI Qiaoling; CHEN Xu; LIU Wenpin
(The Second Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410005,China)
关键词:
冠心病;  心律失常;  温阳复脉益心加减方;  铜砭刮痧;  室性早搏;  心率;  中医证候积分
Keywords:
Coronary heart disease;  Arrhythmology;  Wenyang Fumai Yixin Jiaxian formula;  Copper bian guasha;  Ventricular premature beat;  Heart rate;  Traditional Chinese medicine syndrome score
分类号:
R 541.4
DOI:
DOI:10.3969/j.issn.1000-7369.2024.03.010
文献标志码:
A
摘要:
目的:探究温阳复脉益心加减方联合铜砭刮痧治疗老年冠心病并发心律失常的临床价值。方法:选取冠心病并发心律失常患者94例,依据简单随机数字表法分为中西医组、西医组,各47例。西医组口服胺碘酮、美托洛尔,中西医组在西医组基础上采取温阳复脉益心加减方联合铜砭刮痧,两组均治疗1个月。统计两组治疗前后中医证候积分、临床疗效、心率、短阵室性心动过速数量、室性早搏数量、校正QT间期(QTc)、QT离散度(QTd)、不良反应发生情况。结果:治疗后两组胸闷气短、心悸不安、眩晕、自汗懒言、神疲乏力、形寒肢冷、面色白评分较治疗前下降,且中西医组低于西医组,差异有统计学意义(均P<0.05)。中西医组治疗总有效率93.62%高于西医组78.72%,差异有统计学意义(均P<0.05)。治疗后两组静息心率、24 h最快心率、24 h最慢心率、24 h平均心率、24 h总心率较治疗前增高,且中西医组高于西医组,差异有统计学意义(均P<0.05)。治疗后两组短阵室性心动过速数量、室性早搏数量少于治疗前,且中西医组少于西医组,差异有统计学意义(均P<0.05)。治疗后两组QTc、QTd较治疗前降低,且中西医组低于西医组,差异有统计学意义(均P<0.05)。中西医组不良反应发生率6.38%与西医组10.64%比较,差异无统计学意义(P>0.05)。结论:温阳复脉益心加减方联合铜砭刮痧治疗老年冠心病并发心律失常可改善心率,缓解临床症状,提升治疗效果,且较安全。
Abstract:
Objective:To explore clinical value of Wenyang Fumai Yixin Jiajian prescription combined with Tongbian Guasha in elderly patients with coronary heart disease accompanied by arrhythmia.Methods:94 patients with coronary heart disease accompanied by arrhythmia were selected and divided into traditional Chinese and Western medicine group and Western medicine group,each group 47 cases,according to simple random number table method.The western medicine group took amiodarone and metoprolol,and the traditional Chinese and Western medicine group took Wenyang Fumai Yixin Jiajian prescription and Tongbian Guasha on the basis of the Western medicine group.Both groups were treated for 1 month.TCM syndrome score,clinical efficacy,heart rate,number of short ventricular tachycardia and premature ventricular beats,corrected QT interval(QTc)and QT dispersion(QTd),occurrence of adverse reactions in the two groups before and after treatment were analyzed.Results:After treatment,the scores of chest depression,shortness of breath,palpitation,vertigo,spontaneous sweating,mental fatigue,cold shape and limbs,and facial concentration decreased in the two groups,and the scores of traditional Chinese and western medicine group were lower than those in the western medicine group,difference statistically significant(all P<0.05).The total effective rate of the Chinese and western medicine group 93.62% was higher than that in the Western medicine group 78.72%,difference statistically significant(P<0.05).After treatment,the resting heart rate,24 h fastest heart rate,24 h slowest heart rate,24 h average heart rate and 24 h total heart rate of the two groups were higher than before treatment,and the western medicine group were higher than those in the western medicine group,difference statistically significant(all P<0.05).After treatment,the number of short ventricular tachycardia and premature ventricular beats in the two groups were lower than before treatment,and the number of Chinese and western medicine group were lower than that in the Western medicine group,difference statistically significant(all P<0.05).After treatment,QTc and QTd in the two groups were lower than before treatment,and the western medicine group were lower than those in the western medicine group,difference statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the Chinese and western medicine group 6.38% and the Western medicine group 10.64%(P>0.05).Conclusion:The combination of Wenyang Fumai Yixin Jiajian prescription and Tongbian Guasha in the treatment of elderly coronary heart disease with arrhythmia can improve heart rate,relieve clinical symptoms,improve therapeutic effect of disease,and better safety.

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备注/Memo

备注/Memo:
基金项目:湖南省自然科学基金资助项目(2022JJ30448); 湖南省中医药科研计划项目(C2022031)
更新日期/Last Update: 2024-03-08