[1]牛莹超,任伊宁,兴 伟.疏肝清热方联合微创清创法治疗浆细胞性乳腺炎肝经郁热证临床研究[J].陕西中医,2024,(3):349-353.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.013]
　NIU Yingchao,REN Yining,XING Wei.Clinical study on treatment of plasma cell mastitis liver meridian stagnation heat type with Shugan Qingre formula combined with minimally invasive debridement[J].,2024,(3):349-353.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.013]
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疏肝清热方联合微创清创法治疗浆细胞性乳腺炎肝经郁热证临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年3期
页码:
349-353
栏目:
临床研究
出版日期:
2024-03-05

文章信息/Info

Title:
Clinical study on treatment of plasma cell mastitis liver meridian stagnation heat type with Shugan Qingre formula combined with minimally invasive debridement
作者:
牛莹超; 任伊宁; 兴 伟
(河北中医药大学第一附属医院,河北 石家庄 050011)
Author(s):
NIU Yingchao; REN Yining; XING Wei
(First Affiliated Hospital of Hebei University of Traditional Chinese Medicine,Shijiazhuang 050011,China)
关键词:
浆细胞性乳腺炎;  疏肝清热方;  微创清创法;  炎症因子;  视觉疼痛评分量表
Keywords:
Plasma cell mastitis;  Shugan Qingre formula;  Microwave ablation;  Inflammatory factor;  Visual pain rating scale
分类号:
R 271.1
DOI:
DOI:10.3969/j.issn.1000-7369.2024.03.013
文献标志码:
A
摘要:
目的:观察疏肝清热方联合微创清创法治疗浆细胞性乳腺炎肝经郁热证疗效。方法:选取80例浆细胞性乳腺炎肝经郁热证患者为研究对象,随机分为观察组、对照组,各40例。对照组予微创清创法治疗,观察组加用疏肝清热方治疗,观察并比较两组疗效。结果:治疗后,观察组乳腺肿块最大直径、模拟视觉疼痛评分量表评分低于对照组,差异有统计学意义(均P<0.05)。治疗后,观察组中医证候积分低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组IL-6、TNF-α、hs-CRP低于对照组,差异有统计学意义(均P<0.05)。随访期间观察组复发率低于对照组(P<0.05)。治疗期间,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在浆细胞性乳腺炎肝经郁热证微创清创法治疗后,服用疏肝清热方能够有效缩小乳房肿块,取得较好乳房美容效果,减轻患者乳房疼痛不适及一系列临床症状,并能下调血清炎症因子表达,降低复发率和不良反应,安全性较高。
Abstract:
Objective:Observe clinical efficacy of Shugan Qingre formula combined with minimally invasive debridement treatment for plasma cell mastitis liver meridian stagnation heat type.Methods:80 patients with plasma cell mastitis liver meridian stagnation heat type were admitted as the research subjects.The selected samples were enrolled and allocated equally to the observation and control group,each group included 40 samples.The observation group were received minimally invasive debridement combined with Shugan Qingre formula on the basis of the control group in addition while the control group just received standardroutine treatment.The therapeutic effects of the two groups were observed and compared.Results:After treatment,the maximum diameter of breast mass and the score of simulated visual pain scale in the observation group were lower than those in the control group,differences statistically significant(all P<0.05).After treatment,the TCM syndrome score of the observation group were lower than that in the control group,difference statistically significant(P<0.05).After treatment,IL-6,TNF-α and hs-CRP in the observation group were lower than those in the control group,differences statistically significant(all P<0.05).During follow-up,the recurrence rate of the observation group was lower than that in the control group,differences statistically significant(P<0.05).During treatment,the incidence of adverse reactions compared between the two groups difference was not statistically significant(P>0.05).Conclusion:After the treatment of plasma cell mastitis with minimally invasive debrideation,Shugan Qingre prescription can effectively reduce breast mass,achieve better breast cosmetic effect,reducing breast pain discomfort and series of clinical symptoms of patients,down-regulate expression of serum inflammatory factors and ecurrence rate adverse reactions.It have high safety.

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备注/Memo

备注/Memo:
基金项目:河北省中医药管理局中医药类科研计划课题(2023043)
更新日期/Last Update: 2024-03-08