[1]熊芳冰,王皓冉,叶敦敏.基于“虚气留滞”中医病机假说阐释易栓症致复发性流产[J].陕西中医,2024,(9):1233-1236.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.019]
　XIONG Fangbing,WANG Haoran,YE Dunmin.Explanation of the pathogenesis of recurrent miscarriage due to thrombophilia disease based on the hypothesis of “deficiency of qi and stagnation” in TCM[J].,2024,(9):1233-1236.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.019]
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基于“虚气留滞”中医病机假说阐释易栓症致复发性流产
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年9期
页码:
1233-1236
栏目:
学术探讨
出版日期:
2024-09-05

文章信息/Info

Title:
Explanation of the pathogenesis of recurrent miscarriage due to thrombophilia disease based on the hypothesis of “deficiency of qi and stagnation” in TCM
作者:
熊芳冰1; 王皓冉1; 叶敦敏2
(1.广州中医药大学第三临床医学院,广东 广州 510405; 2.广州中医药大学第三附属医院,广东 广州 510375)
Author(s):
XIONG Fangbing; WANG Haoran; YE Dunmin
(Third School of Clinical Medicine,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China)
关键词:
复发性流产;  易栓症;  虚气留滞;  病因病机;  治疗;  总结
Keywords:
Recurrent spontaneous abortion;  Thrombophilia disease;  Deficiency and stagnation of Qi;  Etiology and pathogenesis;  Treatment;  Conclusion
分类号:
R 714.21
DOI:
DOI:10.3969/j.issn.1000-7369.2024.09.019
文献标志码:
A
摘要:
复发性流产易栓症是人体凝血功能异常所引起的病理状态,中医并无确切名称,高发于育龄期女性,一直是临床治疗的难点与重点。本文结合“虚气留滞”病机理论,分析复发性流产易栓症的病因病机。气血亏虚,脏腑虚弱是其发病的基础,痰湿、气滞、血瘀等病理物质伤及冲任胞络致屡孕屡堕,是其发病依据。“虚气”为本,“留滞”为标,前因后果,相互影响,为复发性流产易栓症提供新的辨病思路。
Abstract:
Recurrent spontaneous abortion and thrombophilia is a pathological condition caused by abnormal coagulation function of the human body.There is no exact name in traditional Chinese medicine.Combined with the pathogenesis theory of “Deficiency of Qi and Stagnation”,this article analyzes the etiology and pathogenesis of recurrent spontaneous abortion and thrombophilia.Qi and blood deficiency and zangfu weakness are the basis of its pathogenesis.Repeated pregnancy and abortion are caused by phlegm dampness,qi stagnation,blood stasis and other pathological substances,as well as the thoroughness of conception and conception vessels.With “deficiency qi” as the root and “retention” as the standard,the causes and consequences affect each other,which provides a new idea for the differentiation of recurrent spontaneous abortion and thrombocytopenia.

参考文献/References:

[1] 自然流产诊治中国专家共识编写组.自然流产诊治中国专家共识(2020年版)[J].中国实用妇科与产科杂志,2020,36(11):1082-1090.
[2] 李洁.2016年中国“复发性流产诊治的专家共识”与2017年欧洲“复发性流产诊治指南”的解读[J].实用妇产科杂志,2018,34(11):822-825.
[3] GRANDONE E,TISCIA G L,MASTROIANNO M,et al.Findings from a multicentre,observational study on reproductive outcomes in women with unexplained recurrent pregnancy loss:The OTTILIA registry[J].Hum Reprod,2021,36(8):2083-2090.
[4] SCHWARZMAN P,PAZ L D,WALFISCH A,et al.Maternal history of recurrent pregnancy loss and long-term risk of thromboembolic events[J].J Reprod Immunol,2020,138:103084.
[5] 谭小方,丁家怡.血栓前状态在胚胎反复种植失败中的研究进展[J].中国妇幼健康研究,2019,30(6):744-748.
[6] HAN A R,HAN J W,LEE S K.Inherited thrombophilia and anticoagulant therapy for women with reproductive failure[J].Am J Reprod Immunol,2021,85(4):e13378.
[7] ORQUEVAUX P,MASSEAU A,GUERN V,et al.In vitro fertilization in 37 women with systemic lupus erythematosus or antiphospholipid syndrome:A Series of 97 procedures[J].J Rheumatol,2017,44(5):613-618.
[8] POTDAR N,GELBAYA T A,KONJE J C,et al.Adjunct low-molecular-weight heparin to improve live birth rate after recurrent implantation failure:A systematic review and meta-analysis[J].Hum Reprod Update,2013,19(6):674-684.
[9] 低分子肝素防治自然流产中国专家共识编写组.低分子肝素防治自然流产中国专家共识[J].中华生殖与避孕杂志,2018,38(9):701-708.
[10] 吴越,李伟莉.从肾虚论治复发性流产子宫内膜容受性不良[J].陕西中医,2023,44(5):626-628.
[11] 李潇,周艳艳.补肾活血方对肾虚血瘀型子宫内膜异位症不孕患者子宫内膜容受性的影响[J].陕西中医,2018,39(3):341-344.
[12] 张永超,黄世敬,王永炎.“虚气留滞”与帕金森病病机探讨[J].北京中医药大学学报,2013,36(12):805-807.
[13] 杨士瀛.仁斋直指方论[M].贵阳:贵州科技出版社,2016:23-26.
[14] 国家妇幼健康研究会生殖免疫学专业委员会专家共识编写组.复发性流产合并血栓前状态诊治中国专家共识[J].中华生殖与避孕杂志,2021,41(10):861-875.
[15] TOTH B,JESCHKE U,ROGENHOFER N,et al.Recurrent miscarriage:Current concepts in diagnosis and treatment[J].J Reprod Immunol,2010,85(1):25-32.
[16] 中华医学会妇产科学分会产科学组.复发性流产诊治的专家共识[J].中华妇产科杂志,2016,51(1):3-9.
[17] 唐亮,胡豫.《易栓症诊断与防治中国指南(2021版)》更新解读[J].临床血液学杂志,2022,35(7):457-460.
[18] 陈恩荣,吴玉萍,汪丽萍.妊娠合并抗磷脂综合征诊疗进展[J].妇产与遗传:电子版,2018,8(4):48-53.
[19] 王冰唐.黄帝内经素问[M].北京:人民卫生出版社,1963:15-16.
[20] 费伯雄.医醇賸义[M].北京:人民卫生出版社,2023:32-35.
[21] 丹波元简.灵枢识[M].北京:中国医药科技出版社,2019:124-126.
[22] 朱震亨.格致余论[M].北京:中国中医药出版社,2021:127-128.
[23] 张景岳.景岳全书[M].北京:中国医药科技出版社,2011:36-39.
[24] 韩萍,于春蕾,马文香,等.基于治未病理论谈无症状疾病从血浊论治[J].天津中医药,2020,37(6):609-612.
[25] 彭丽,李佩瑶,胡小芳.胡小芳教授治疗易栓症致复发性流产经验浅探[J].中国中医药现代远程教育,2023,21(8):146-148.

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备注/Memo

备注/Memo:
基金项目:广东省中医药局科研项目(20233024)
更新日期/Last Update: 2024-09-09