[1]徐雨霏,高 杰,夏联恒,等.柴麻复脉汤治疗下肢深静脉血栓形成脾虚湿阻证临床研究[J].陕西中医,2025,46(4):481-485.[doi:DOI:10.3969/j.issn.1000-7369.2025.04.010]
　XU Yufei,GAO Jie,XIA Lianheng,et al.Clinical observation of Chaima Fumai decoction in treating lower extremity deep venous thrombosis with spleen deficiency and dampness obstruction syndrome[J].,2025,46(4):481-485.[doi:DOI:10.3969/j.issn.1000-7369.2025.04.010]
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柴麻复脉汤治疗下肢深静脉血栓形成脾虚湿阻证临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年4期
页码:
481-485
栏目:
临床研究
出版日期:
2025-04-20

文章信息/Info

Title:
Clinical observation of Chaima Fumai decoction in treating lower extremity deep venous thrombosis with spleen deficiency and dampness obstruction syndrome
作者:
徐雨霏1; 高 杰2; 夏联恒2; 崔 璇2; 李 媛3; 胥 可1; 刘启明1; 袁 艺1; 潘明华1
(1.黑龙江中医药大学研究生院,黑龙江 哈尔滨 150000; 2.黑龙江中医药大学附属第一医院周围血管病一科,黑龙江 哈尔滨 150000; 3.黑龙江省第二医院,黑龙江 哈尔滨 150000)
Author(s):
XU Yufei1; GAO Jie2; XIA Lianheng2; CUI Xuan2; LI Yuan3; XU Ke1; LIU Qiming1; YUAN Yi1; PAN Minghua1
(1.Heilongjiang University of Chinese Medicine,Harbin 150000,China; 2.The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150000,China; 3.The Second Hospital of Heilongjiang Province,Harbin 150000,China)
关键词:
下肢深静脉血栓形成;  脾虚湿阻证;  迁延期;  红外热成像技术;  柴麻复脉汤;  血液流变学
Keywords:
Lower extremity deep venous thrombosis;  Spleen deficiency and dampness obstruction syndrome;  Prolonged stage;  Infrared thermography;  Chaima Fumai decoction;  Hemorheology
分类号:
R 543.6
DOI:
DOI:10.3969/j.issn.1000-7369.2025.04.010
文献标志码:
A
摘要:
目的:探讨柴麻复脉汤治疗下肢深静脉血栓形成(LDVT)脾虚湿阻证的临床疗效。方法:收集诊断为LDVT且中医辨证为脾虚湿阻证患者60例,按照随机数字表简单随机化法分为对照组与治疗组各30例。在一般治疗的基础上,对照组采用马栗种子提取物片口服治疗,治疗组采用柴麻复脉汤口服治疗,疗程3周。分别对比两组治疗前后中医证候积分、血管腔再通情况、下肢皮肤温度,并测量比较患肢周径,检测白细胞计数、凝血功能指标(FIB、D-D)、全血还原黏度(高切、中切、低切)、血浆黏度指标。结果:与治疗前相比,治疗后两组患者中医证候积分、血管腔再通情况、血栓区与对侧皮肤温差、下肢周径差、白细胞计数、凝血功能指标、全血还原黏度及血浆黏度明显改善,且治疗组各指标改善显著优于对照组(均P<0.05)。治疗组总有效率显著高于对照组(P<0.05)。结论:柴麻复脉汤治疗LDVT疗效较好,能改善患者临床症状与体征,减轻炎症反应,改善凝血功能及血液流变学,且安全性好。
Abstract:
Objective:To investigate the clinical efficacy of Chaima Fumai decoction in the treatment of lower extremity deep venous thrombosis(LDVT)with spleen deficiency and dampness obstruction syndrome.Methods:A total of 60 patients with LDVT with spleen deficiency and dampness obstruction syndrome were randomly divided into a control group and a treatment group,with 30 patients in each group,using a simple randomization method based on a random number table.On the basis of general treatment,the control group received oral administration of Willitan,while the treatment group received oral administration of Chaima Fumai decoction for a course of 3 weeks.The TCM syndrome scores,vascular recanalization rate,skin temperature of the lower extremities,the circumference of the lower limb,WBC,coagulation function indicators(FIB,D-D)and hemorheology(whole blood reduced viscosity and plasma viscosity indicators)were compared before and after treatment.Results:Compared with before treatment,the TCM syndrome scores,vascular recanalization rate,skin temperature of the lower extremities,the circumference of the lower limb,WBC,coagulation function indicators(FIB,D-D)and hemorheology were significantly improved in both groups,the improvement in all indicators in the treatment group was significantly better than that in the control group(all P<0.05).The total effective rate in the treatment group was significantly higher than that in the control group(P<0.05).Conclusion:Chaima Fumai decoction has good efficacy in the treatment of LDVT,can improve clinical symptoms and signs of patients,reduce inflammation,improve coagulation function and hemorheology,and has good safety.

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备注/Memo

备注/Memo:
[基金项目]黑龙江省自然科学基金资助面上项目(H2015045)
更新日期/Last Update: 2025-04-08