[1]潘雯,陈开运,陈元岩.针刺联合双柏散外敷治疗急性胰腺炎临床研究[J].陕西中医,2025,46(6):839-843.[doi:DOI:10.3969/j.issn.1000-7369.2025.06.025]
　PAN Wen,CHEN Kaiyun,CHEN Yuanyan.Clinical observation on the efficacy of acupuncture combined with external application of Shuangbai powder in treating acute pancreatitis[J].,2025,46(6):839-843.[doi:DOI:10.3969/j.issn.1000-7369.2025.06.025]
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针刺联合双柏散外敷治疗急性胰腺炎临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年6期
页码:
839-843
栏目:
针灸经络
出版日期:
2025-06-05

文章信息/Info

Title:
Clinical observation on the efficacy of acupuncture combined with external application of Shuangbai powder in treating acute pancreatitis
作者:
潘雯; 陈开运; 陈元岩
（广州中医药大学附属广州中西医结合医院，广东 广州 510800)
Author(s):
PAN Wen; CHEN Kaiyun; CHEN Yuanyan
(Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510800,China)
关键词:
急性胰腺炎; 针刺; 双柏散; 中医证候; 炎症指标; 胃肠功能
Keywords:
Acute pancreatitis; Acupuncture; Shuangbai powder; TCM syndrome; Inflammatory indices; Gastrointestinal function
分类号:
R 575.1
DOI:
DOI:10.3969/j.issn.1000-7369.2025.06.025
文献标志码:
A
摘要:
目的：探究针刺疗法联合双柏散外敷对急性胰腺炎（AP）患者的干预效果。方法：本研究共纳入98例AP患者，遵循随机数字表法将其分配至对照组与观察组，各49例。对照组进行禁食、止痛、抗感染及营养支持等常规治疗，观察组加用针刺联合双柏散外敷治疗。两组治疗周期均为7 d。研究主要观察指标包括：治疗前后主要生化指标、炎症相关指标改善情况，胃肠功能恢复情况、中医证候评分变化及总体临床疗效评估。结果：观察组在胃肠功能恢复情况上均显著优于对照组（P<0.05）。治疗后，两组患者的主要生化指标（血清淀粉酶、血清脂肪酶）以及炎症相关指标白介素-1β（IL-1β）、C反应蛋白（CRP）、降钙素原（PCT）、肿瘤坏死因子-α（TNF-α）和中医证候积分均较前改善，观察组的改善程度显著优于对照组（P<0.05）。在临床疗效方面，观察组的总有效率95.92%，显著高于对照组的81.63%（P<0.05）。结论：针刺疗法联合双柏散外敷可显著促进急性胰腺炎患者的胃肠功能恢复，有效降低炎症指标水平，改善中医证候，并显著提高临床疗效。
Abstract:
Objective:Exploring the intervention effect of acupuncture therapy combined with Shuangbai powder external application on patients with acute pancreatitis (AP).Methods:This study enrolled a total of 98 AP patients,who were allocated to the control group and the observation group using a random number table method,with 49 cases in each group.The control group received conventional therapy including fasting,analgesia,anti-infective treatment,and nutritional support,while the observation group was additionally administered acupuncture combined with external application of Shuangbai powder.Both groups were treated for 7 days.The main observation indicators included: changes in key biochemical markers (serum amylase,serum lipase) before and after treatment;improvements in inflammation-related markers [interleukin-1β (IL-1β),C-reactive protein (CRP),procalcitonin (PCT),tumor necrosis factor-α (TNF-α)];gastrointestinal function recovery (abdominal pain relief time,bowel sound recovery time,first defecation time);changes in traditional Chinese medicine (TCM) syndrome scores;and overall clinical efficacy evaluation.Results:The observation group showed significantly better gastrointestinal function recovery than the control group (P<0.05).After treatment,both groups exhibited significant reductions in key biochemical markers (serum amylase,serum lipase),inflammation-related markers (IL-1β,CRP,PCT,TNF-α),and TCM syndrome scores compared to pre-treatment levels,with a more pronounced reduction in the observation group (P<0.05).In terms of clinical efficacy,the total effective rate in the observation group was 95.92%,significantly higher than the control group’s 81.63% (P<0.05).Conclusion:Acupuncture therapy combined with Shuangbai powder external application can significantly promote gastrointestinal function recovery,effectively reduce inflammatory marker levels,improve TCM syndromes,and enhance clinical efficacy in patients with acute pancreatitis.

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备注/Memo

备注/Memo:
广东省自然科学基金资助项目（2023A1515220212）；广东省中医药局科研项目(20171221)
更新日期/Last Update: 2025-06-09