[1]王宏静,韩蕊,甄维帅,等.中医综合疗法治疗痰湿质高尿酸血症的效果及对患者血清尿酸、血脂水平的影响[J].陕西中医,2025,46(12):1650-1654.[doi:DOI:10.3969/j.issn.1000-7369.2025.12.013]
　WANG Hongjing,HAN Rui,ZHEN Weishuai,et al.The impact of comprehensive traditional chinese medicine therapy on serum ua and LDL-C levels in patients with phlegm-dampness constitution hyperuricemia[J].,2025,46(12):1650-1654.[doi:DOI:10.3969/j.issn.1000-7369.2025.12.013]
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中医综合疗法治疗痰湿质高尿酸血症的效果及对患者血清尿酸、血脂水平的影响

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年12期
页码:
1650-1654
栏目:
临床研究
出版日期:
2025-12-05

文章信息/Info

Title:
The impact of comprehensive traditional chinese medicine therapy on serum ua and LDL-C levels in patients with phlegm-dampness constitution hyperuricemia
作者:
王宏静; 韩蕊; 甄维帅; 陈嫚嫚
（中国中医科学院广安门医院济南医院 济南市中医医院，山东 济南 250012）
Author(s):
WANG Hongjing; HAN Rui; ZHEN Weishuai; CHEN Manman
(Guang’anmen Hospital Jinan Hospital，Jinan Traditional Chinese Medicine Hospital，Jinan 250012,China)
关键词:
高尿酸血症; 中医体质; 治未病; 痰湿质; 中药足浴; 耳穴压豆
Keywords:
Hyperuricemia; TCM constitution; Preventive treatment of disease; Phlegm dampness constitution; Chinese medicine foot bath; Auricular acupoint bean pressing
分类号:
R 589
DOI:
DOI:10.3969/j.issn.1000-7369.2025.12.013
文献标志码:
A
摘要:
目的：观察中医综合疗法（中药足浴+耳穴压豆+八段锦）治疗痰湿质高尿酸血症（HUA）的效果及对患者血清血尿酸（UA），低密度脂蛋白胆固醇（LDL-C），总胆固醇（TC）水平的影响。方法：将100例符合痰湿质HUA诊断标准的受试者。根据随机分配原则将研究对象按1∶1分为试验组和对照组。对照组50例患者采取常规健康干预，在其基础上试验组50例患者采用中医综合疗法，两组均干预3个月。观察干预前后的痰湿体质积分、UA、LDL-C、TC及体重指数（BMI）等指标，统计两组干预期间不良反应发生情况。结果：试验组总有效率明显优于对照组（P＜0.001）。干预3个月后，试验组痰湿体质症状（胸脘痞闷、口中黏腻、多汗且黏、便溏不爽、身困乏力、头重如裹、痰多）积分、疾病相关因子（UA、LDL-C、TC）明显低于干预前及同期对照组（P<0.001），BMI两组内治疗后差异有显著统计学意义（P＜0.001）。两组均未见不良反应。结论：运用中医“治未病”理念综合疗法治疗痰湿质HUA具有显著效果，能够有效改善患者症状，并降低痰湿体质症状积分及血清UA、LDL-C、TC水平。
Abstract:
Objective：To evaluate the efficacy of a comprehensive traditional Chinese medicine (TCM) therapy (herbal foot bath + auricular acupoint bean pressing + Baduanjin exercise) in treating hyperuricemia with phlegm-dampness constitution and its effects on serum uric acid (UA)， low-density lipoprotein cholesterol (LDL-C)，Total Cholesterol (TC) levels.Methods:A total of 100 participants diagnosed with hyperuricemia and identified as having a phlegm-dampness constitution were participants were randomly assigned to two groups in a 1∶1 ratio.50 cases in the control group received routine health interventions, while 50 cases in the experimental group was treated with the comprehensive TCM therapy in addition to the routine interventions for 3 months. Phlegm-dampness constitution scores, serum UA, LDL-C levels,TC，body mass index (BMI) and adverse reactions were observed and compared before and after the intervention.Results:Compared with the therapeutic effect of the control group, the total effective rate of the experimental group was better (P<0.001).Following 3 months of intervention, the experimental group presented with prominent decreases in phlegm-dampness symptoms constitution symptom scores (chest/stomach stuffiness, sticky mouth sensation, sticky sweating, loose stools, fatigue, heavy-headedness, and excessive phlegm) and disease-related factors (UA, LDL-C，TC) compared to both baseline and the control group (P<0.001)，There were statistically significant differences in BMI within both groups before and after treatment (P<0.001).No adverse reactions were observed in either group.Conclusion:The application of the TCM “preventive treatment of disease” concept through comprehensive therapy significantly improves symptoms, reduces phlegm-dampness constitution scores, and lowers serum UA and LDL-C and TC levels in patients with hyperuricemia and phlegm-dampness constitution.

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备注/Memo

备注/Memo:
国家中医药管理局中医药标准化项目[SATCM-2015-BZ(367)]；山东省济南市卫生健康委科技计划项目（2023-中-5）
更新日期/Last Update: 2025-12-08