[1]卞旭东,陈正光,李小圳,等.调心通督针刺治疗房颤合并轻度认知障碍疗效研究[J].陕西中医,2026,(5):682-686.[doi:DOI:10.3969/j.issn.1000-7369.2026.05.019]
　BIAN Xudong,CHEN Zhengguang,LI Xiaozhen,et al.Clinical study of Tiaoxin Tongdu acupuncture for atrial fibrillation with mild cognitive impairment[J].,2026,(5):682-686.[doi:DOI:10.3969/j.issn.1000-7369.2026.05.019]
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调心通督针刺治疗房颤合并轻度认知障碍疗效研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2026年5期
页码:
682-686
栏目:
针灸经络
出版日期:
2026-05-05

文章信息/Info

Title:
Clinical study of Tiaoxin Tongdu acupuncture for atrial fibrillation with mild cognitive impairment
作者:
卞旭东1; 陈正光1; 李小圳1; 赵天佐1; 钟利群1; 卫景沛1; 杜丰夷2; 李杰留2; 张晶晶2; 郭 静3
（1.北京中医药大学东直门医院，北京 100700；2.北京中医药大学，北京 100029；3.首都医科大学附属北京中医医院，北京 100011）
Author(s):
BIAN Xudong1; CHEN Zhengguang1; LI Xiaozhen1; ZHAO Tianzuo1; ZHONG Liqun1; WEI Jingpei1; DU Fengyi2; LI Jieliu2; ZHANG Jingjing2; GUO Jing3
（1.Dongzhimen Hospital of Beijing University of Chinese Medicine,Beijing 100700,China；2.Beijing University of Chinese Medicine,Beijing 100029,China；3.Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100011,China）
关键词:
房颤; 轻度认知障碍; 调心通督; 针刺疗法; 认知功能; 白细胞介素-6; 肿瘤坏死因子-α
Keywords:
Atrial fibrillation; Mild cognitive impairment; Tiaoxin Tongdu; Acupuncture; Cognitive function; Interleukin-6; Tumor necrosis factor-α
分类号:
R541
DOI:
DOI:10.3969/j.issn.1000-7369.2026.05.019
文献标志码:
A
摘要:
目的：探讨调心通督针刺法治疗房颤合并轻度认知障碍的临床疗效。方法：选取68例房颤合并轻度认知障碍患者，采用随机数字表法分为观察组与对照组，各34例。两组均予基础药物治疗和认知功能康复训练，观察组同时予调心通督针刺法治疗。比较两组临床疗效，观察两组治疗前后平均心室率、蒙特利尔认知评估量表(MoCA)评分、Rivermead行为记忆测验(RBMT)评分、连线测验-A(TMT-A)结果、连线测验-B(TMT-B)结果以及白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平的变化。结果：观察组总有效率高于对照组(P＜0.05)。治疗后，两组MoCA、RBMT评分均高于同组治疗前(P＜0.05)，且观察组评分高于对照组(P＜0.05)。两组TMT-A、TMT-B用时均少于同组治疗前(P＜0.05)，且观察组用时少于对照组(P＜0.05)。两组平均心室率、IL-6、TNF-α水平均低于同组治疗前(P＜0.05)，且观察组上述指标优于对照组(P＜0.05)。结论：在基础药物治疗和认知功能康复训练的同时，应用调心通督针刺法能有效降低房颤合并轻度认知障碍患者的心室率，改善整体认知功能，提高记忆力、注意力及执行力，调节血清IL-6和TNF-α水平。
Abstract:
Objective:To explore clinical efficacy of acupuncture method of regulating the heart and unblocking the governor meridian in the treatment of atrial fibrillation (AF) combined with mild cognitive impairment (MCI).Methods:A total of 68 patients with AF and MCI were selected and rando mly divided into an observation group and a control group,with 34 cases in each group.Both groups were given basic drug treatment and cognitive function rehabilitation training,while the observation group was also treated with the acupuncture method of regulating the heart and unblocking the governor meridian.The clinical efficacy of the two groups were compared,and the changes in average ventricular rate,montreal cognitive assessment(MoCA) score,rivermead behavioural memory test(RBMT) score,trail making test part A (TMT-A) results,trail making test part B (TMT-B) results,and levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) before and after treatment were observed.Results:The total effective rate of the observation group was higher than that in the control group (P＜0.05).After treatment,the MoCA and RBMT scores of both groups were higher than those before treatment (P＜0.05),and the scores of the observation group were higher than those in the control group (P＜0.05).The TMT-A and TMT-B times of both groups were shorter than those before treatment (P＜0.05),and the times of the observation group were shorter than those in the control group (P＜0.05).The average ventricular rate,IL-6,and TNF-α levels of both groups were lower than those before treatment (P＜0.05),and the above indicators of the observation group were better than those in the control group (P＜0.05).Conclusion:In addition to basic drug treatment and cognitive function rehabilitation training,the application of the acupuncture method of regulating the heart and unblocking the governor meridian can effectively reduce the ventricular rate of patients with AF and MCI,improve overall cognitive function,enhance memory,attention,and executive function,and regulate the levels of serum IL-6 and TNF-α.

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相似文献/References:

[1]孙婷婷,魏 哲,郑书敏,等.自主神经调控房颤的作用机制及中医药治疗研究进展*[J].陕西中医,2019,(1):135.
　SUN Tingting,WEI zhe,Zheng Shumir,et al.The machanism of regulateion of autonomic nervous system in atrial fibrillation and the research progress about The traditional Chinese medicine[J].,2019,(5):135.

备注/Memo

备注/Memo:
国家自然科学基金资助项目（82174339，82374568）；北京市自然科学基金资助项目（7232291）；北京市中医药管理局中医药质量控制管理项目（BJZYY202411）；北京中医药大学揭榜挂帅重点项目（2024-JYB-JBZD-002）
更新日期/Last Update: 2026-05-05