[1]李鸿,徐无忌△.加味身痛逐瘀汤治疗骨质疏松椎体压缩性骨折经皮穿刺椎体成形术后残余痛临床研究*[J].陕西中医杂志,2019,(11):1545-1547，1551.
　LI Hong,XU Wuji..Clinical observation on residual pain after PVP in the treatment of osteoporotic vertebral compression fracture with Jiawei Shentong Zhuyu decoction[J].,2019,(11):1545-1547，1551.
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加味身痛逐瘀汤治疗骨质疏松椎体压缩性骨折经皮穿刺椎体成形术后残余痛临床研究*
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《陕西中医》杂志[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年11期
页码:
1545-1547，1551
栏目:
临床研究
出版日期:
2019-11-05

文章信息/Info

Title:
Clinical observation on residual pain after PVP in the treatment of osteoporotic vertebral compression fracture with Jiawei Shentong Zhuyu decoction
文章编号:
DOI:10.3969/j.issn.10007369.2019.11.016
作者:
李鸿1; 徐无忌2△
1.湖南中医药大学（长沙 410208）；2.湖南中医药大学第二附属医院（长沙 410008）
Author(s):
LI Hong;  XU Wuji.
Hunan University of Traditional Chinese Medicine（Changsha 410008）
关键词:
身痛逐瘀汤; 经皮穿刺椎体成形术; 骨质疏松; 椎体压缩性骨折; 术后残余痛; 疼痛视觉模拟评分
Keywords:
Key words Shentong Zhuyu decoction; PVP; Osteoporosis; Vertebral compression fracture; Postoperative residual pain; VAS
分类号:
R683.2
文献标志码:
A
摘要:
摘要目的：观察加味身痛逐瘀汤治疗骨质疏松椎体压缩性骨折经皮穿刺椎体成形术(PVP)后残余痛患者的临床疗效。方法：将64例患者随机分为观察组和对照组，每组32例，观察组予以口服加味身痛逐瘀汤，对照组为空白对照组，观察治疗前及规范服药后1 d、7 d、14 d、1月后的疼痛视觉模拟评分(VAS评分) 、血瘀证评分及ODI指数的变化程度，以此来判别治疗疗效。结果：两组在治疗后1 d时VAS及ODI较治疗前有统计学意义（P＜005），而血瘀证在治疗后1 d时与治疗前比较无统计学意义（P＞005）,在治疗后7 d、14 d、1月时，ODI指数、血瘀证评分及VAS评分均有统计学意义（P＜005），组间对比时，两组在治疗前，治疗后1 d及治疗后1月时无统计学意义(P＞005),治疗后7 d及治疗后14 d时，两组比较有统计学意义（P＜005），观察组优于对照组（P＜005），并且通过相关性分析，VAS评分及ODI指数与血瘀证评分有显著的相关性（其相关系数分别为r=0.906、0.975）。结论：PVP手术是一种能治疗OVCF快速有效的方法，但对患者术后瘀血证候无明显改善作用，身痛逐瘀汤通过促进机体对瘀血的吸收从而加快患者术后残余痛的恢复。
Abstract:
AbstractObjective:To observe the clinical effect of modified Shentong Zhuyu decoction on residual pain after PVP for osteoporotic vertebral compression fracture.Methods:64 patients were randomly divided into two groups (observation group and control group),32 in each group.The observation group was given Shentong Zhuyu decoction orally,while the control group was given blank control group.The visual analogue score of pain (VAS score) and blood were observed before treatment and 1 day,7 days,14 days and 1 month after standard medication.The changes of blood stasis score and ODI index were used to judge the therapeutic effect.Results:There were significant differences in VAS and ODI between the two groups at 1 day after treatment (P＜005),but there was no significant difference in blood stasis syndrome at 1 day after treatment (P＞005),ODI index,blood stasis syndrome score and VAS score at 7 days,14 days and 1 month after treatment (P＜005).There was no significant difference between the two groups before treatment,one day after treatment and one month after treatment (P＞005).At 7 days and 14 days after treatment,there was significant difference between the two groups (P＜005).The observation group was better than the control group (P＜005) when compared with the control group.Through correlation analysis,VAS score,ODI index and blood stasis syndrome score were significant.The correlation coefficients were r=0.906 and 0.975,respectively.Conclusion:PVP is a quick and effective method to treat OVCF,but it can not alleviate the symptoms of blood stasis after operation.The occurrence of residual pain after operation is closely related to blood stasis.Shentong Zhuyu decoction can accelerate the recovery of residual pain after operation by promoting the absorption of blood stasis by the body.

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备注/Memo

备注/Memo:
*国家自然科学基金青年科学基金资助项目（81302993） 湖南省中医药科技计划重点项目（201317）
更新日期/Last Update: 2019-11-15