[1]樊海元,林砚铭,巫 斌△.川芎茶调散合身痛逐瘀汤加减配合针灸治疗坐骨神经痛疗效研究*[J].陕西中医杂志,2020,(2):206-209.
　FAN Haiyuan,LIN Yanming,WU Bin..Curative effect of Chuanxiong Chatiaosan and Modified Shengtong Zhuyu decoction combined with acupuncture on sciatica[J].,2020,(2):206-209.
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川芎茶调散合身痛逐瘀汤加减配合针灸治疗坐骨神经痛疗效研究*
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《陕西中医》杂志[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年2期
页码:
206-209
栏目:
临床研究
出版日期:
2020-02-05

文章信息/Info

Title:
Curative effect of Chuanxiong Chatiaosan and Modified Shengtong Zhuyu decoction combined with acupuncture on sciatica
文章编号:
DOI:〖HT5K〗10.3969/j.issn.10007369.2020.02.018
作者:
樊海元1; 林砚铭2; 巫 斌1△
1.成都市青白江区中医医院外一科(成都 610306); 2.成都中医药大学附属医院骨科(成都 610075)
Author(s):
FAN Haiyuan; LIN Yanming; WU Bin.
The First Department of External Medicine,Qingbaijiang District Hospital of Traditional Chinese Medicine(Chengdu 610306)
关键词:
川芎茶调散;  身痛逐瘀汤;  针灸;  坐骨神经痛;  疗效
Keywords:
Chuanxiong Chatiaosan;  Shengtong Zhuyu decoction;  Acupuncture;  Sciatica;  Curative effect
分类号:
R745.42
文献标志码:
A
摘要:
目的:探讨川芎茶调散合身痛逐瘀汤加减配合针灸治疗坐骨神经痛的疗效。方法:选取坐骨神经痛患者共153例,对照组75例接受常规西药及针灸治疗,观察组78例在其基础上加用川芎茶调散合身痛逐瘀汤加减治疗,比较两组临床总有效率、神经传导速度、疼痛程度评分及致痛物质水平。结果:观察组总有效率89.74%(70/78)显著高于对照组73.33%(55/75,P<0.05); 观察组腓肠神经感觉神经传导速度SCV、腓肠神经运动神经传导速度MCV及病变侧胫神经运动神经传导速度MCV显著高于对照组(P<0.05); 观察组腰骶部、臀部、大腿外侧、腘窝、小腿外侧VAS评分显著低于对照组(P<0.05); 观察组血浆5-羟色胺(5-HT)和P物质(SP)水平显著低于对照组(P<0.05)。结论:川芎茶调散合身痛逐瘀汤加减配合针灸治疗坐骨神经痛具有良好的临床疗效,能够对有效提高患者神经传导速度,减少致痛物质的合成及分泌,缓解疼痛。
Abstract:
Objective:To explore curative effect of Chuanxiong Chatiaosan and modified Shengtong Zhuyu decoction combined with acupuncture on sciatica.Methods:78 sciatica patients who were admitted to rehabilitation department were enrolled as observation group.75 sciatica patients who were admitted to rehabilitation department were enrolled as control group.The control group was given routine western medicine and acupuncture treatment.On this basis,observation group was additionally given Chuanxiong Chatiao san and modified Shengtong Zhuyu decoction.The total clinical response rate,nerve conduction velocity,pain degree score and levels of pain-causing substances were compared between the two groups.Results:The total response rate of observation group was significantly higher than that of control group [89.74%(70/78)vs 73.33%(55/75)](P<0.05).The sensory conduction velocity(SCV)of sural nerve,motor conduction velocity(MCV)of sural nerve,and MCV of tibial nerve at lesion side in observation group were significantly higher than those in control group(P<0.05).VAS scores at lumbosacral region,buttock,lateral thigh,popliteal fossa,and lateral calf in observation group were significantly lower than those in control group(P<0.05).The levels of plasma serotonin(5-HT)and substance P(SP)in observation group were significantly lower than those in control group(P<0.05).Conclusion:The clinical curative effect of Chuanxiong Chatiao san and modified Shengtong Zhuyu decoction combined with acupuncture is good on sciatica,which can effectively improve nerve conduction velocity,reduce synthesis and secretion of pain-causing substances,and relieve pain.

参考文献/References:

[1] 李胜吾,戴国钢,秦雪飞,等.动气针法治疗中老年腰椎间盘突出症坐骨神经痛33例[J].南京中医药大学学报,2016,32(2):138-141.
[2] 李 波,孙岳枫,李德东,等.富氢液对糖尿病神经痛大鼠坐骨神经TLR4/NF-κB信号通路的影响[J].中华麻醉学杂志,2015,35(10):1231-1234.
[3] 李 磊,李乃杰,辛冬梅,等.通痹止痛方结合针刺治疗60例根性坐骨神经痛[J].中国实验方剂学杂志,2014,20(20):206-209.
[4] 苗润青,晋 松.针刺为主治疗腰椎间盘突出症所致坐骨神经痛研究进展[J].陕西中医,2015,36(2):254-256.
[5] 国家食品药品监督管理总局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:212-213.
[6] 邱 玲.针刺坐骨神经干治疗腰椎间盘突出症所致坐骨神经痛的疗效观察[J].针刺研究,2016,41(5):447-450.
[7] 罗雅尹,宋春莉,汤奇祯,等.原发性睾丸淋巴瘤复发致以坐骨神经痛为表现的神经淋巴瘤一例[J].中华神经科杂志,2018,51(6):470-472.
[8] 王福朝,赵海蕊,陈金辉,等.地佐辛不同给药方式在腰丛-坐骨神经联合阻滞中镇痛效果的比较[J].广东医学,2017,38(18):2862-2864.
[9] 刘艳平,李引刚,LIU YP,等.腰痛宁胶囊治疗寒湿瘀阻型坐骨神经痛临床疗效观察[J].中草药,2015,46(19):2916-2918.
[10] 孙 达,许保海.川芎茶调散治疗偏头痛的疗效观察及对β内啡肽、五羟色胺的影响[J].中国中医急症,2016,25(11):2117-2119.
[11] 杜旌畅,谢晓芳,熊 亮,等.川芎挥发油的化学成分与药理活性研究进展[J].中国中药杂志,2016,41(23):4328-4333.
[12] Jun C,Qiu DJ,Ye MW,et al.Potential of essential oils as penetration enhancers for transdermal administration of ibuprofen to,treat dysmenorrhoea[J].Molecules,2015,20(10):18219-18236.
[13] 王 佳,王 钢,王 涛,等.身痛逐瘀汤联合西药治疗类风湿关节炎瘀血痹阻证的临床观察[J].中国实验方剂学杂志,2017,12(24):185-189.
[14] 张景锋,李文龙,顿国亮,等.探讨超声检查在诊断腕管综合征中的应用价值[J].陕西医学杂志,2016,45(4):472-473.
[15] 韦 平,徐丹婷,陈宇峰,等.黄芪桂枝五物汤抗大鼠坐骨神经痛的药效学研究[J].科学技术与工程,2016,16(19):170-173.
[16] 沈源彬,关宏刚,曹正霖,等.加味身痛逐瘀汤预防腰椎术后综合征发生及对血清TNF-α水平的影响[J].中国中西医结合杂志,2014,34(7):800-803.
[17] 张 希,刘 萍.骨性关节炎所致慢性持续性疼痛的发病机制[J].中国骨质疏松杂志,2017,23(2):248-255.
[18] 刘建平,郑保平,刘凤恩,等.身痛逐瘀汤加减辅助治疗下肢动脉硬化闭塞症介入术后缺血灌注损伤的研究[J].中国中西医结合杂志,2017,37(8):1014-1015.
[19] 王 倩,付文玉,庄文欣,等.血管活性肠肽对帕金森病大鼠中缝背核5-HT、SP、CRF及CRFR2表达的影响[J].神经解剖学杂志,2015,31(5):611-616.

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备注/Memo

备注/Memo:
*国家自然科学基金资助项目(81574027)；四川省教育厅基金资助项目(18ZB0195)
更新日期/Last Update: 2020-03-31