[1]孙一凡,赵敏,郑泽泉,等.基于玄府学说探讨升清降浊法治疗脑病[J].陕西中医,2025,46(11):1531-1534,1539.[doi:DOI:10.3969/j.issn.1000-7369.2025.11.016]
　SUN Yifan,ZHAO Min,ZHENG Zequan,et al.Application of ascending lucidity and reducing turbidity in encephalopathy based on the Xuanfu theory[J].,2025,46(11):1531-1534,1539.[doi:DOI:10.3969/j.issn.1000-7369.2025.11.016]
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基于玄府学说探讨升清降浊法治疗脑病
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年11期
页码:
1531-1534,1539
栏目:
学术探讨
出版日期:
2025-11-05

文章信息/Info

Title:
Application of ascending lucidity and reducing turbidity in encephalopathy based on the Xuanfu theory
作者:
孙一凡1; 赵敏2 ; 郑泽泉2; 招远祺2
（1.广东省中医院珠海医院，广东 珠海 519000；2.广东省中医院，广东 广州 510120）
Author(s):
SUN Yifan1; ZHAO Min2; ZHENG Zequan2; ZHAO Yuanqi2
（1.Zhuhai Hospital of Guangdong Provincial Hospital of Chinese Medicine，Zhuhai 519000，China；2.Guangdong Provincial Hospital of Chinese Medicine，Guangzhou 510120，China）
关键词:
玄府学说; 升清降浊; 神机; 脑病; 病机; 辨证论治
Keywords:
Xuanfu theory; Ascending lucidity and reducing turbidity; Vital activity; Encephalopathy; Pathogenesis; Syndrome differentiation and treatment
分类号:
R 742
DOI:
DOI:10.3969/j.issn.1000-7369.2025.11.016
文献标志码:
A
摘要:
疑难及罕见脑病病机复杂，与机体多个系统关系密切，相互影响。随着现代医学发展，越来越多疑难及罕见脑病被诊断，但是当前仍缺乏有效治疗手段，对人类的生命健康带来巨大威胁，迫切需要极本穷源探索新的治疗思路与方法。玄府极细极小，广泛分布于人体内外各处结构，是气血津液精升降出入的运行通路，亦是人体最先受邪之处。玄府贵开忌阖，玄府通利为清升浊降的生理机制，为正常运行提供了基础，二者相互影响，对于维持神机正常运转具有决定性意义。现代医学研究提示，血脑屏障、微循环、离子通道、信号通路等与玄府在结构和功能上有诸多相似之处，可能是玄府学说的科学内涵，为玄府学说在疑难及罕见脑病中的应用提供了有力支持。基于玄府学说，从中医经典出发，结合临床实践和名家经验，深入分析疑难及罕见脑病病理发展过程，提出“清浊相干，玄府郁闭，神机失用”为其核心病机，并提出基于“升清降浊法”开通玄府，恢复神机的治疗思路，指出玄府郁闭与清浊相干相互影响，互为因果，疑难及罕见脑病以玄府微小病变为肇始，存在由量变向质变发展的病理过程，构建“玄府-升清降浊-神机”微观辨证体系”，强调微观辨证与未病先防，为疑难及罕见脑病的中医治疗提供新的治疗思路与临床借鉴。
Abstract:
The pathogenesis of intractable and rare brain diseases is complex,closely related to multiple systems of the body with mutual interactions.With the advancement of modern medicine,increasing number of such diseases are being diagnosed.However,effective treatment methods remain lacking,posing significant threats and challenges to human life and health.There is an urgent need to explore new therapeutic approaches by tracing the root causes.Xuanfu are extremely fine and widely distributed throughout internal and external structures of the human body.They serve as pathways for the ascending,descending,entering,and exiting movements of Qi,blood,body fluids essence,and are also the first sites where pathogens invade.Xuanfu favor openness and dislike closure.Their unobstructed flow provides foundation for the normal physiological mechanisms of clear Qi ascending and turbid Qi descending.These two aspects influence each other and play a decisive role in maintaining the proper functioning of Shenji.Modern medical research suggests that blood-brain barrier,microcirculation,ion channels,and signaling pathways share many structural and functional similarities with the Xuanfu,which may represent the scientific essence of Xuanfu theory.This provides strong support for the application of the Xuanfu theory in intractable and rare brain diseases.Based on the Xuanfu theory and drawing from classical Chinese medicine,combined with clinical practice and the expertise of renowned physicians,this study conducts an in-depth analysis of the pathological progression of intractable and rare brain diseases.It proposes that interference between clear and turbid Qi,obstruction of Xuanfu,and dysfunction of the Shenji constitutes the core pathogenesis.Furthermore,it introduces therapeutic approach centered on the ascending clear and descending turbid method to unblock Xuanfu and restore Shenji.The study highlights that obstruction of the Xuanfu and interference between clear and turbid Qi influence each other,forming a vicious cycle.Intractable and rare brain diseases often originate from minute lesions in the Xuanfu,progressing from quantitative changes to qualitative transformations.A microscopic syndrome differentiation system of Xuanfu-ascending clear and descending turbid-Shenji is constructed,emphasizing microscopic syndrome differentiation and preventive treatment before disease onset.This provides new therapeutic insights and clinical references for the treatment of intractable and rare brain diseases using traditional Chinese medicine.

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备注/Memo

备注/Memo:
广东省基础与应用基础研究基金资助项目（2022A1515220134）；广东省中医药局科研项目（20221166）；国家中医药管理局高水平中医药重点学科建设项目（ZYYZDXK-2023154）
更新日期/Last Update: 2025-11-04