[1]王 玥,黄 雷,张 婷.针灸联合丁苯酞治疗大面积脑梗死术后早期疗效研究[J].陕西中医,2022,(3):367-370.[doi:DOI:10.3969/j.issn.1000-7369.2022.03.024]
　WANG Yue,HUANG Lei,ZHANG Ting.Clinical effect of acupuncture with butylphthalide on early intervention after large-scale cerebral infarction[J].,2022,(3):367-370.[doi:DOI:10.3969/j.issn.1000-7369.2022.03.024]
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针灸联合丁苯酞治疗大面积脑梗死术后早期疗效研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年3期
页码:
367-370
栏目:
针灸经络
出版日期:
2022-03-05

文章信息/Info

Title:
Clinical effect of acupuncture with butylphthalide on early intervention after large-scale cerebral infarction
作者:
王 玥; 黄 雷; 张 婷
(湖南中医药大学第一附属医院,湖南 长沙 410007)
Author(s):
WANG Yue; HUANG Lei; ZHANG Ting
(The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410007,China)
关键词:
脑梗死;  针灸;  丁苯酞软胶囊;  早期干预;  血流动力学
Keywords:
Cerebral infarction;  Acupuncture;  Butylphthalide;  Early intervention;  Hemodynamics
分类号:
R 255.2
DOI:
DOI:10.3969/j.issn.1000-7369.2022.03.024
文献标志码:
A
摘要:
目的:探讨针灸联合丁苯酞软胶囊对大面积脑梗死术后早期干预的临床疗效。方法:将98例大面积脑梗死术后患者分为观察组和对照组,每组49例,对照组采用常规治疗,观察组在对照组基础上给予针灸联合丁苯酞软胶囊治疗。比较两组临床疗效、神经功能、生活质量及颅内血流动力学。结果:观察组治疗总有效率为87.76%,高于对照组的71.43%(P<0.05)。治疗后,两组患者美国国立卫生研究院卒中量表(NIHSS)评分较治疗前下降(P<0.05),Barthel指数评分(BI)、SF-36生活质量量表评分较治疗前升高(均P<0.05),且观察组各项评分改善程度优于对照组(均P<0.05)。治疗后,两组患者大脑前动脉(ACA)、中动脉(MCA)平均血流速度均较治疗前升高,且观察组ACA、MCA平均血流速度高于对照组(均P<0.05)。结论:针灸联合丁苯酞软胶囊对大面积脑梗死术后患者进行早期干预疗效较好,有助于改善患者脑血流动力学和神经功能损伤,提高日常生活能力及生活质量。
Abstract:
Objective:To investigate the clinical effect of acupuncture with butylphthalide on early intervention after large-scale cerebral infarction.Methods:98 cases of patients with large-scale cerebral infarction after operation were divided into observation group and control group,49 cases in each group.The control group received conventional treatment,and the observation group was given acupuncture with butylphthalide treatment on the basis of the control group.The clinical effect,neurological function,quality of life and intracranial hemodynamics were compared between the two groups.Results:The total effective rate of the observation group was 87.76%,significantly higher than 71.43% of the control group(all P<0.05).After treatment,NIHSS scores in the two groups were decreased compared with before treatment(all P<0.05),while BI and SF-36 scores were increased compared with before treatment(all P<0.05).The improvement of scores in the observation group was better than that in the control group(all P<0.05).After treatment,the mean flow velocity of ACA and MCA in the two groups were increased compared with before treatment,and the mean flow velocity of ACA and MCA in the observation group were higher than those in the control group(all P<0.05).Conclusion:The early intervention of acupuncture with butylphthalide and moxibustion in patients with large-scale of cerebral infarction was effective,which was helpful to improve the state of cerebral hemodynamics and neurological damage,improve the ability of daily life and quality of life.

参考文献/References:

[1] 詹少英,师雯琦.脑梗死患者流行病学不可控危险因素的相关分析[J].心血管外科杂志:电子版,2020,9(2):146-147.
[2] 韩 毅,邓文涛,刘 洋.开颅去骨瓣减压联合颞极或(和)额极切除内减压术治疗大面积脑梗死的效果观察[J].中国医师杂志,2020,22(4):610-612.
[3] 邹敏刚,罗德芳,杨瑞金,等.标准去骨瓣减压联合内减压术对大面积脑梗死患者血流动力学及预后的影响[J].天津医药,2020,48(11):1059-1064,1137.
[4] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南[J].中华神经科杂志,2015,48(4):246-257.
[5] 劳祎林,吴 林,伍 媛,等.中医药疗法应用于脑梗死恢复期的研究进展[J].广西医学,2019,41(16):2102-2104.
[6] 赵建国,高长玉,顼宝玉,等.脑梗死和脑出血中西医结合诊断标准[J].中国中西医结合杂志,2006,26(10):948-949.
[7] 侯东哲,张 颖,巫嘉陵,等.中文版美国国立卫生院脑卒中量表的信度与效度研究[J].中华物理医学与康复杂志,2012,34(5):372-374.
[8] 巫嘉陵,安中平,王世民,等.脑卒中患者日常生活活动能力量表的信度与效度研究[J].中国现代神经疾病杂志,2009,9(5):464-468.
[9] 杨小湜,王 阳,李秀君,等.SF-36量表的信度和效度评价[J].解剖科学进展,2009,15(4):383-385.
[10] 李 强,周腾飞,贺迎坤,等.急诊血管内治疗急性前循环大面积脑梗死的疗效及影响因素分析[J].中华神经医学杂志,2020,19(7):671-676.
[11] 巩 超,金香兰.大面积脑梗死的治疗进展[J].中华老年心脑血管病杂志,2019,21(3):334-336.
[12] 詹 燕,刘佩军,肖承承,等.丁苯酞软胶囊对中青年缺血性卒中患者认知功能的影响[J].中国新药杂志,2017,26(13):1546-1550.
[13] 陈海恋,何超明,庞明武,等.丁苯酞治疗老年急性脑梗死的疗效及对细胞因子和神经功能的影响[J].中华老年心脑血管病杂志,2016,18(11):1173-1177.
[14] 杨东娜,张 涤,于佳佳.丁苯酞注射液联合依达拉奉对老年急性脑梗死患者细胞因子、血管内皮功能和氧化应激的影响[J].中国老年学杂志,2021,41(3):477-480.
[15] 齐凡星,胡 莹,卢军栋,等.丁苯酞对大鼠神经细胞凋亡的保护作用及其机制研究[J].贵州医药,2016,40(11):1132-1134.
[16] 夏道宽,蒋同伯,杨道海.温针灸对脑梗死恢复期气虚血瘀型患者炎性因子、神经因子及高凝状态的影响[J].陕西中医,2020,41(10):1485-1488.
[17] 杨 龙,李兴琼,晏四斤.芪参还五胶囊配合针灸对大面积脑梗死术后早期干预的临床研究[J].现代中西医结合杂志,2020,29(10):1119-1122.
[18] 陈 佳,陶 红,陈小欢,等.醒脑开窍针对急性脑梗死的疗效及部分机制探讨[J].世界中医药,2020,15(3):468-472.
[19] 刘艳华,张 静,孙 艳,等.针灸联合康复治疗对脑梗死患者神经功能恢复、血清细胞因子分泌的影响[J].世界中医药,2019,14(9):2488-2491.
[20] 刘雷婧,陈国芳,平 蕾,等.急性脑梗死血流动力学临床分析[J].内蒙古医科大学学报,2019,41(4):374-376.
[21] 夏 辉,祁占宁,王 飒,等.急性脑梗死患者血浆Hcy、血管内皮功能和血流动力学的改变及意义[J].中南医学科学杂志,2019,47(3):311-314.
[22] 闫 俊,常 嵘,李伟旺,等.大脑中动脉重度狭窄侧支循环对脑梗死发病机制及NIHSS评分的影响[J].陕西医学杂志,2017,46(12):1636-1637.

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备注/Memo

备注/Memo:
基金项目:湖南省自然科学基金资助项目(2020JJ8066)
更新日期/Last Update: 2022-03-09