[1]薛美昊,许龙鑫,田萍,等.中药调控免疫细胞抗肺癌作用机制研究进展[J].陕西中医,2026,(1):126-132.[doi:DOI:10.3969/j.issn.1000-7369.2026.01.023]
　XUE Meihao,XU Longxin,TIAN Ping,et al.Research progress on the mechanisms of Chinese medicine in regulating immune cells for anti-lung cancer effects[J].,2026,(1):126-132.[doi:DOI:10.3969/j.issn.1000-7369.2026.01.023]
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中药调控免疫细胞抗肺癌作用机制研究进展

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2026年1期
页码:
126-132
栏目:
综 述
出版日期:
2026-01-05

文章信息/Info

Title:
Research progress on the mechanisms of Chinese medicine in regulating immune cells for anti-lung cancer effects
作者:
薛美昊1; 许龙鑫1; 田萍1; 郭琼琼1; 杨靖宁1; 东旭超1; 李金田1; 梁建庆2; 胡蓉1
（1.甘肃中医药大学中医临床学院，甘肃 兰州 730000；2.甘肃中医药大学基础医学院，甘肃 兰州730000）
Author(s):
XUE Meihao1; XU Longxin1; TIAN Ping1; GUO Qiongqiong1; YANG Jingning1; DONG Xuchao1; LI Jintian1; LIANG Jianqing2; HU Rong1
（1.Clinical College of Traditional Chinese Medicine,Gansu University of Chinese Medicine,Lanzhou 730000，China；2.School of Basic Medicine,Gansu University of Chinese Medicine，Lanzhou 730000，China）
关键词:
肺癌; 中药; 免疫细胞; 作用机制; 免疫微环境
Keywords:
Lung cancer; Traditional Chinese medicine; Immune cells; Mechanisms of action; Tumor immune microenvironment
分类号:
R 734.2
DOI:
DOI:10.3969/j.issn.1000-7369.2026.01.023
文献标志码:
A
摘要:
肺癌是全球最常见且致死率最高的癌症，免疫治疗为肿瘤治疗提供了新的方向。在肿瘤免疫微环境中，免疫细胞如T细胞、NK细胞、巨噬细胞、树突状细胞及髓源抑制细胞等，发挥着至关重要的作用。这些免疫细胞通过相互作用共同维持机体对肿瘤的免疫监视与攻击功能。近年来，越来越多的研究表明，中药单体成分（如多糖类、皂苷类、生物碱类、萜类和黄酮类等活性成分）及中药复方（如四君子汤、金复康、肺金生方、养阴温阳方、温阳散结加减方等）能够通过多途径调节免疫细胞功能，从而有效增强抗肿瘤免疫反应，为肿瘤的治疗提供了新的思路。
Abstract:
Lung cancer is the most common and deadliest cancer worldwide,and immunotherapy has provided a new direction for tumor treatment.In the tumor immune microenvironment,immune cells such as T cells,NK cells,macrophages,dendritic cells,and myeloid-derived suppressor cells play a crucial role.These immune cells interact with each other to maintain the body’s immune surveillance and attack functions against tumors.In recent years,increasing research has shown that active ingredients from traditional Chinese medicine (such as polysaccharides,saponins,alkaloids,terpenes,flavonoids,etc.) and Chinese herbal formulas (such as Sijunzi Tang,Jinfukang,Feijinsheng Fang,Yangyin Wenyang Fang,Wenyang Sanjie Fang,etc.) can regulate immune cell functions through multiple pathways,thereby effectively enhancing anti-tumor immune responses and offering new approaches for tumor treatment.

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备注/Memo

备注/Memo:
国家自然科学基金资助项目（82160872）;甘肃省教育厅“双一流”科研重点项目（GSSYLXM-05）：甘肃道地药材产业关键技术及其组方的基础与开发应用研究;甘肃省中医药研究中心开放课题（ZYZX-2020-ZX17）
更新日期/Last Update: 2026-01-08