[1]江 晟,陆 敏 .肠康方治疗腹泻型肠易激综合征临床研究*[J].陕西中医,2019,(3):331-334.
　JIANG Sheng,LU Min..Clinical observation of Changkang prescription in treating predominant irritable bowel syndrome[J].,2019,(3):331-334.
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肠康方治疗腹泻型肠易激综合征临床研究*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年3
页码:
331-334
栏目:
临床研究
出版日期:
2019-03-05

文章信息/Info

Title:
Clinical observation of Changkang prescription in treating predominant irritable bowel syndrome
文章编号:
DOI: 10.3969/j.issn.10007369.2019.03.017
作者:
江 晟1; 陆 敏 2
1.南京中医药大学第三临床医学院（南京 210046）;2.江苏省中西医结合医院（南京 210028）
Author(s):
JIANG Sheng;  LU Min.
Nanjing University of Traditional Chinese Medicine, Third Clinical Medical College（Nanjing 210046）
关键词:
肠易激综合征; 中医药疗法; 肠康方; 马来酸曲美布汀; 腹泻; 疗效比较研究
Keywords:
Key words Irritable bowel syndrome; Traditional Chinese medicine therapy; Changkang prescription; Trimebutine maleate; Diarrhea; Comparative effectiveness research
分类号:
R257.3
文献标志码:
A
摘要:
摘 要 目的：观察肠康方治疗腹泻型肠易激综合征的临床疗效。方法：将60例肠易激综合征患者随机分为两组,治疗组30例,口服中药肠康方治疗,并随证加减，每日1剂，早晚分服，每次约200 ml，疗程4周，治疗前后完善IBSSSS量表。对照组30例,口服马来酸曲美布汀胶囊,每次0.1 g,3次/d,疗程4周，治疗前后完善IBSSSS量表。结果：治疗后两组患者各项评分均有下降，治疗组总有效22例，无效8例，临床总有效率为73.33%。对照组总有效18例，无效12例，临床总有效率为60.00%。在改善患者腹痛程度、腹痛频率方面肠康方与马来酸曲美布汀胶囊疗效相当，两组比较无统计学差异(P＞0.05)。在改善患者腹胀程度、排便满意度、对生活影响方面肠康方均优于马来酸曲美布汀胶囊，两组比较有统计学差异（P0.05）。结论：肠康方治疗腹泻型肠易激综合征具有临床意义，能有效改善患者腹痛程度、腹痛频率、腹胀程度、排便满意度及对生活影响，与马来酸曲美布汀胶囊比较在改善腹胀、排便满意度、对生活影响方面更有优势。
Abstract:
Abstract Objective: To observe the clinical efficacy of Changkang prescription in the treatment of diarrhea predominant irritable bowel syndrome. Methods: 60 patients with irritable bowel syndrome were randomly divided into two groups. The treatment group (30 cases) was treated with Changkang presripxtion, one dose a day, taking about 200 ml each time in the morning and evening, and the course of treatment was 4 weeks. The control group (30 cases) was treated with trimebutine maleate capsule 0.1 g each time, and the course of treatment was 4 weeks before and after treatment, Good IBSSSS scale. Results: After treatment, the scores of the two groups decreased, the total effective number of 22 patients in the treatment group, 8 ineffective, the total clinical effective rate was 73.33%, the total effective number of 18 patients in the control group, ineffective 12 patients, the total clinical effective rate was 60.00%. There was no significant difference between the two groups (P0.05).Improving the degree of abdominal pain, abdominal pain frequency, Changkang. Changkang recipe was superior to trimebutine maleate capsule in improving the degree of abdominal distention, defecation satisfaction and life influence, and there was significant difference between the two groups (P0.05). Conclusion: Changkang prescription recipe has clinical significance in treating diarrheapredominant irritable bowel syndrome. It can effectively improve the degree of abdominal pain, frequency of abdominal pain, degree of abdominal distension, degree of defecation satisfaction and its impact on life. Compared with trimebutine maleate capsule, Changkang recipe has more advantages in improving abdominal distension, defecation satisfaction and life impact.It is suitable for clinical use.

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备注/Memo

备注/Memo:
*江苏省自然科学基金（BK20161608） 江苏省中医药科技重大项目（ZD201708） 第十四批“六大人才高峰”项目（WSN040）
更新日期/Last Update: 2019-03-13