[1]王颖.益气降糖饮联合胰岛素对妊娠期糖尿病孕妇血糖、 内脂素水平及妊娠结局的影响*[J].陕西中医杂志,2018,(10):1342-1344，1458.
　Wang Ying..Effects of Yiqi Jiangtang decoction combined with insulin on blood glucose， visfatin level and pregnancy outcome in patients with gestational diabetes mellitus[J].,2018,(10):1342-1344，1458.
点击复制

益气降糖饮联合胰岛素对妊娠期糖尿病孕妇血糖、 内脂素水平及妊娠结局的影响*
分享到：

《陕西中医》杂志[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年10期
页码:
1342-1344，1458
栏目:
临床研究
出版日期:
2018-12-31

文章信息/Info

Title:
Effects of Yiqi Jiangtang decoction combined with insulin on blood glucose， visfatin level and pregnancy outcome in patients with gestational diabetes mellitus
文章编号:
DOI: 10.3969/j.issn.1000-7369.2018.10.007
作者:
王颖
河南省信阳市中心医院妇产科（信阳 464000）
Author(s):
Wang Ying.
Department of Obstetrics and Gynecology，Xinyang Central Hospital in Henan Province（ Xinyang 464000）
关键词:
糖尿病; 妊娠/中西医结合疗法补气剂/治疗应用胰岛素血糖@益气降糖饮
Keywords:
Key words Diabetes; gestational/integrated Chinese traditional and western medicine therapyQi-reinforcing agents/ therapeuticusesInsulin Blood glucose@Yiqi Jiangtang decoction
分类号:
R714.256
文献标志码:
A
摘要:
摘要 目的：探讨益气降糖饮联合胰岛素对妊娠期糖尿病孕妇血糖、内脂素水平及妊娠结局的影响。方法：将124例GDM患者作为研究对象，随机分为对照组（62例）与观察组（62例）。对照组患者给予饮食控制、运动指导和胰岛素注射治疗，观察组患者在此基础上联合益气降糖饮治疗，14 d为1个疗程。对两组患者血糖、内脂素水平及妊娠结局进行对比分析，并评价临床治疗效果。结果：治疗前，两组FPG、2h FPG、HbA1C、血清内脂素水平和中医证候积分无差异（P＞0.05）；治疗后，两组FPG、2h FPG、HbA1C、血清内脂素水平和中医证候积分均有明显下降， 观察组明显低于对照组（P＜0.05）。观察组治疗总有效率90.32%明显高于对照组75.81%（P＜0.05）。观察组剖宫产率，羊水异常、子痫前期、妊娠期高血压、酮症酸中毒等发生率均明显低于对照组（P＜0.05）。观察组巨大儿、呼吸窘迫、早产、高胆红素血症等发病率明显低于对照组（P＜0.05）。结论：益气降糖饮联合胰岛素对妊娠期糖尿病孕妇具有良好的治疗效果，能够显著控制血糖和内脂素水平，有效改善妊娠结局。
Abstract:
Abstract Objective: To investigate the effect of the Yiqi Jiangtang decoction and insulin therapy on blood glucose，alfatin level and pregnancy outcome in patients with gestational diabetes.Methods: A total of 124 GDM patients selected and randomly divided into control group (62 cases) and observation group (62 cases).The control group were treated with diet control，exercise guidance and insulin treatment，the observation group based on the combined use of the Yiqi Jiangtang Decoction . 14d for 1 courses.The blood glucose，the level of endomalin and the outcome of pregnancy were compared and analyzed in the two groups，and the effect of clinical treatment was evaluated.Results: Before treatment，there was no difference between the two groups of FPG，2h FPG，HbA1C，serum lipoprotein level and TCM syndrome score (P＞0.05).After treatment，the levels of FPG，2h FPG，HbA1C，serum visfatin and TCM syndrome scores in the two groups were significantly decreased，which was significantly lower in the observation group than in the control group (P＜0.05).The total effective rate of treatment in the observation group was 90.32% significantly higher than that of the control group (75.81%)(P＜0.05).The rate of cesarean section，abnormal amniotic fluid，preeclampsia，pregnancy induced hypertension and ketoacidosis were significantly lower in the observation group than in the control group (P＜0.05). The incidence of macrosomia，respiratory distress，preterm labor and hyperbilirubinemia in the observation group was significantly lower than that of the control group (P＜0.05).Conclusion: The Yiqi Jiangtang decoction combined with insulin therapy has a good therapeutic effect on pregnant women with gestational diabetes mellitus，which can significantly control the level of blood sugar and visfatin，and effectively improve the outcome of pregnancy.

参考文献/References:


[1] 朱崇月,王文玲,张娅娣,等. 胰岛素联合中药治疗妊娠糖尿病对患者血清内脂素、视黄醇结合蛋白4及hs-CRP水平的影响[J]. 医疗装备,2016,29(2):20-21.
[2]唐国珍,张小霞,谭爱香,等. 盐酸二甲双胍与门冬胰岛素联合治疗对妊娠期糖尿病孕妇血清胱抑素C、同型半胱氨酸及母婴结局的影响[J]. 中国现代医学杂志,2016,26(2):76-79.
[3]朱崇月,王文玲,张娅娣,等. 胰岛素联合中药方治疗对妊娠糖尿病患者分娩结局及母婴预后的影响[J]. 医疗装备,2016,29(7):27-28.
[4]马士侠,姚洁,丛林. 三种妊娠期糖尿病诊断标准在临床中的诊断价值[J]. 中国妇幼保健,2011,26(16):2548-2550.
[5]国家食品药品监督管理局. 中药新药临床研究指导原则[M]. 中国医药科技出版社，2002.：256-257.
[6]魏小辉，王育璠. 2015年国际妇产科联盟(FIGO)妊娠期糖尿病诊疗指南解读[J]. 中华内分泌代谢杂志，2016，32(11):895-899.
[7]吴文娟,姚圣菊,陈茜,等. 胰岛素联合格列本脲对妊娠期糖尿病孕妇血清HbA1c、CysC水平及母婴结局的影响[J]. 中国现代药物应用,2017,11(16):117-119.
[8]姜琳. 低碳水化合物饮食干预在2型糖尿病患者血糖管理中的应用[J].实用临床医药杂志,2017,21(4):64-66.
[9]王浩阳,章福彬. 妊娠期不同糖耐量状况对妊娠结局的影响[J]. 蚌埠医学院学报,2017,42(3):345-347.
[10]冯利霞,王立红,徐颖华,等. 七味白术散联合胰岛素泵短期强化干预治疗脾虚型妊娠期糖尿病临床疗效及对母婴结局的影响[J]. 中医药导报,2014,20(15):78-80.
[11]方新华,卢晓,吴国清. 葛根素对妊娠期糖尿病大鼠调节血脂和抗氧化作用的实验研究[J]. 中华中医药学刊,2016,34(6):1504-1507.
[12]刘奕,陈洁,池丽芳. 益气养阴组方对妊娠期糖尿病的疗效观察及母婴围产结局的影响[J]. 中国临床药理学与治疗学,2013,18(4):408-412.

相似文献/References:

[1]罗荔.降糖饮联合西药治疗儿童1型糖尿病44例[J].陕西中医杂志,2016,(10):1299.
[2]单亮亮,邓小敏,王振刚,等.五味消渴方治疗糖尿病机理探析[J].陕西中医杂志,2017,(06):783.
[3]王巍,赵平.参芪麦味地黄汤联合运动疗法对妊娠期糖尿病气阴两虚型患者 糖脂代谢及妊娠结局的影响*[J].陕西中医杂志,2018,(10):1339.
[4]张 新.益气养血汤联合痔炎冲洗灵治疗肛周脓肿合并糖尿病患者切开〖JZ〗对口引流挂线术后创面愈合的影响[J].陕西中医杂志,2019,(3):368.
[5]刘 辉,王连伟,乔 飞,等.知柏地黄汤联合个体化营养支持治疗糖尿病合并肺结核疗效及对患者T淋巴细胞亚群的影响*[J].陕西中医杂志,2019,(1):76.
[6]杨 敏,姜钧文,肖 蕾.中医体质与急性心肌梗死及其危险因素的相关性研究*[J].陕西中医杂志,2019,(4):437.
　YANG Min,JIANG Junwen,XIAO Lei..Study on the correlation between constitution of traditional Chinese medicine and acute myocardial infarction and its risk factors[J].,2019,(10):437.
[7]秦福芳,阎 磊,申凤娟,等.血必净注射液治疗老年糖尿病合并急性肾盂肾炎疗效研究[J].陕西中医杂志,2019,(4):456.
　QIN Fufang,SHEN Fengjuan,SHAO Fengmin..Effect of Xuebijing injection on acute pyelonephritis in elderly patients with diabetes[J].,2019,(10):456.
[8]刘 扬,韩家凯,王 前.麝香养心散治疗糖尿病合并冠状动脉粥样硬化性心脏病 及对患者血脂、血流变与凝血功能的影响*[J].陕西中医杂志,2019,(5):576.
　LIU Yang,HAN Jiakai,WANG Qian..Effect of Shexiang Yangxin powder on diabetic mellitus complicated with coronary atherosclerotic heart disease and its influence on blood lipid, hemorheological index and coagulation function〖WT4”BZ〗[J].,2019,(10):576.
[9]何 丽,朱亚丽,罗 方,等.盐酸帕罗西汀片联合养阴益气中药治疗糖尿病合并抑郁症 疗效研究*[J].陕西中医杂志,2019,(5):645.
　HE Li,ZHU Yali,LUO Fang,et al.Effects of paroxetine hydrochloride tablets combined with Yangyin Yiqi TCM on SDS，DQOL and TESS score in diabetic patients with depression[J].,2019,(10):645.
[10]冯国英,曾纪斌,陈玉甜.玉液汤加减治疗2型糖尿病疗效及对患者β细胞功能、颈动脉内中膜厚度的影响[J].陕西中医杂志,2019,(9):1244.

备注/Memo

备注/Memo:
*河南省医学科技攻关计划项目(201503227)
更新日期/Last Update: 2019-01-07