[1]袁华均,冯云亮,向 杰,等.宣气活血方对腰椎间盘突出症单侧双通道脊柱内镜术后疗效的影响[J].陕西中医,2024,(3):358-361,398.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.015]
 YUAN Huajun,FENG Yunliang,XIANG Jie,et al.Study on curative effect of Xuanqi Huoxue prescription in treatment of lumbar disc herniation after unilateral double-channel spinal endoscopy[J].,2024,(3):358-361,398.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.015]
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宣气活血方对腰椎间盘突出症单侧双通道脊柱内镜术后疗效的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年3期
页码:
358-361,398
栏目:
临床研究
出版日期:
2024-03-05

文章信息/Info

Title:
Study on curative effect of Xuanqi Huoxue prescription in treatment of lumbar disc herniation after unilateral double-channel spinal endoscopy
作者:
袁华均冯云亮向 杰王 毅
(南充市中医医院 筋骨病中医药防治南充市重点实验室,四川 南充 637000)
Author(s):
YUAN HuajunFENG YunliangXIANG JieWANG Yi
(Nanchong Key Laboratory of Chinese Medicine Prevention and Treatment of Sinew Diseases,Nanchong Hospital of Traditional Chinese Medicine,Nanchong 637000,China)
关键词:
腰椎间盘突出症 宣气活血方 单侧双通道脊柱内镜 疼痛递质 腰椎功能 生物力学性能 疼痛
Keywords:
Lumbar disc herniation Xuanqi Huoxue formula Unilateral two-channel spinal endoscopy Pain transmitter Lumbar spine function Biomechanical properties Pain
分类号:
R 274.34
DOI:
DOI:10.3969/j.issn.1000-7369.2024.03.015
文献标志码:
A
摘要:
目的:观察宣气活血方治疗腰椎间盘突出症单侧双通道脊柱内镜(UBE)术后患者疼痛递质及腰背肌生物力学性能的影响。方法:选取130例腰椎间盘突出症患者为对象,采用随机数字表法分为两组。两组均接受UBE治疗,常规组术后给予常规处理。方剂组术后在常规处理基础上给予宣气活血方辅助治疗。检测两组血清疼痛递质、腰背肌生物力学性能差异,评估两组视觉模拟(VAS)评分、Oswestry(ODI)评分、日本骨科协会(JOA)评分、中医证候评分变化,记录两组并发症和疗效。结果:与本组术前比较,两组术后2周血清疼痛递质明显下降,且方剂组低于常规组(P<0.05)。与本组术前比较,两组术后12周腰背屈伸比明显下降,且方剂组低于常规组(P<0.05)。与本组术前比较,两组术后12周前降力距、平均功率明显升高,且方剂组高于常规组(P<0.05)。与本组术前比较,两组术后2、12周VAS评分、ODI评分、中医证候评分明显下降,且方剂组低于常规组(P<0.05)。治疗后两组术后2、12周JOA评分升高,且方剂组高于常规组(P<0.05)。方剂组并发症率低于常规组(P>0.05)。结论:宣气活血方治疗腰椎间盘突出症UBE术后可抑制血清疼痛递质表达,减轻疼痛,改善腰椎功能,提高优良率。
Abstract:
Objective:To observe the effects of Xuanqi Huoxue formula on pain transmitters and biomechanical properties of lumbar muscle after unilateral double-channel spinal endoscopy(UBE)in patients with lumbar disc herniation.Methods:130 patients with lumbar disc herniation were selected and divided into two groups by random number method.Both groups received UBE treatment,and the conventional group received routine treatment after surgery.The prescription group was given Xuanqi Huoxue adjuvant treatment on the basis of routine treatment.The differences of serum pain transmitters and the biomechanical properties of lumbar and back muscles between the two groups were detected,the changes of visual analogue scale(VAS)score,Oswestry(ODI)score,Japanese Orthopaedic Association(JOA)score and TCM syndrome score between the two groups were evaluated,and the complications and curative effects of the two groups were recorded.Results:Compared to preoperative,the serum pain transmitter in the two groups was significantly decreased 2 weeks after surgery,and the prescription group was lower than the conventional group(P<0.05).Compared to preoperative,the lumbar and back flexion and extension ratio of the two groups was significantly decreased 12 weeks after surgery,and the prescription group was lower than the conventional group(P<0.05).Compared to preoperative,the descending pitch and average power of the two groups were significantly increased 12 weeks after surgery,and the prescription group was higher than the conventional group(P<0.05).Compared to preoperative,VAS score,ODI score and TCM syndrome score of 2 and 12 weeks after surgery were significantly decreased,and the prescription group was lower than the conventional group(P<0.05).After treatment,the JOA score of 2 and 12 weeks after surgery was significantly increased,and the prescription group was higher than the conventional group(P<0.05).The complication rate of the prescription group was lower than that of the conventional group,and there was no statistical difference between the good and good rate and the conventional group(P>0.05).Conclusion:Xuanqi Huoxue formula can inhibit the expression of pain transmitter in serum,relieve pain,improve lumbar function and increase the good and good rate after UBE.

参考文献/References:

[1] HASVIK E,HAUGEN A J,GROVLE L.Pinprick and light touch are adequate to establish sensory dysfunction in patients with lumbar radicular pain and disc herniation[J].Clinical Orthopaedics and Related Research,2021,479(4):651-663.
[2] 郑明军,蒋臻,张植雄,等.经皮椎间孔镜技术与显微镜辅助治疗腰椎间盘突出症的临床疗效分析[J].中国内镜杂志,2023,29(4):13-18.
[3] 吴利,张静,黄曾,等.586例腰椎间盘突出症患者中医体质分类与证型分布的研究[J].中国中医急症,2022,31(12):2170-2172.
[4] 中华医学会放射学分会介入学组.腰椎间盘突出症的介入和微创治疗操作规范的专家共识[J].中华放射学杂志,2014,48(1):10-12.
[5] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:65.
[6] 孙兵,车晓明.视觉模拟评分法[J].中华神经外科杂志,2012,28(6):645.
[7] 刘绮,麦明泉,肖灵君,等.中文版Oswestry功能障碍指数评定慢性腰痛患者的反应度研究[J].中国康复医学杂志,2010,25(7):521-524.
[8] 孙兵,车晓明.日本骨科协会评估治疗[J].中华神经外科杂志,2012,12(6):623.
[9] 葛郁龙,康银辉.术前坐骨神经传导速度与腰椎间盘突出症经皮椎间孔镜下椎间盘切除治疗效果相关性研究[J].陕西医学杂志,2022,51(10):1253-1255.
[10] BROOKS M,DOWER A J,MUHAMMAD F A,et al.Radiological predictors of recurrent lumbar disc herniation:A systematic review and meta-analysis[J].Journal of Neurosurgery,2021,34(3):481-491.
[11] 曹奔,郭光昕,朱清广,等.导引功法防治腰椎间盘突出症研究进展[J].世界中医药,2021,16(10):1633-1637.
[12] BERNSTEIN D N,MERCHAN N,FEAR K,et al.Greater socioeconomic disadvantage is associated with worse symptom severity at initial presentation in patients seeking care for lumbar disc herniation[J].Spine,2021,46(7):464-471.
[13] PAULSEN R T,CARREON L,ANDERSEN M O.Patient-reported outcomes after surgery for lumbar disc herniationa randomized controlled trial comparing the effects of referral to municipal physical rehabilitation versus no referral[J].Spine,2020,45(1):3-9.
[14] 杜京庭,苏清伦,程明达.基于MRI分析腰椎间盘突出症中医证型与病理的相关性[J].中国CT和MRI杂志,2022,20(9):175-176,188.
[15] 王人彦,张杰,赵睿晞,等.骨伤名师张玉柱治疗腰椎间盘突出症的临床经验[J].中国中医骨伤科杂志,2020,28(2):80-81.
[16] 俞鹏飞,马智佳,姜宏.中医药保守治疗脱出/游离型腰椎间盘突出症促进重吸收的临床实践与思考[J].上海中医药杂志,2022,56(7):18-21.
[17] 石芸,毛银雪,金俊杰,等.牛蒡子炮制前后质量标志物的网络药理学研究[J].科学技术与工程,2020,20(32):13123-13128.
[18] 谢泽宇,许一笑,郑梦圆,等.基于网络药理学探究合欢皮-白蒺藜药对抑制肝星状细胞系LX2的抗焦亡作用[J].中国中药杂志,2023,48(2):481-491.
[19] 廖禹程,丁一,王文军,等.基于网络药理学探讨独活镇痛的分子作用机制[J].中国药师,2021,24(1):1-6.
[20] 常智跃,王慧珍,张彦辉,等.针刺运动疗法联合体外冲击波治疗腰椎间盘突出症临床研究[J].陕西中医,2023,44(5):652-654.
[21] 张君,孙思勉,赵琳,等.普通和冻干三七粉的有效成分及药理作用比较[J].河北大学学报(自然科学版),2020,40(3):269-275,282.
[22] 张金磊,王怀新,喻景奕,等.两种腰椎间盘切除术式神经传导与疼痛介质比较[J].中国矫形外科杂志,2021,29(17):1621-1623.
[23] 王淅克,黄岩石,郑铁牛.LDH患者PGE2、5-HT及炎症细胞介质的变化与患者疼痛的关系[J].实验与检验医学,2020,38(1):152-155.
[24] 朱笑举,潘锋,陈妍蓓,等.电针“梨状二穴”对腰椎间盘突出症大鼠NPY、SP及神经节的影响[J].云南中医中药杂志,2022,43(5):66-70.
[25] 张巍,吴永东,李祎,等.脊柱微创髓核摘除术对腰椎间盘突出症患者血清TXB2、PGE2、IL-6水平及腰椎功能的影响[J].中华老年骨科与康复电子杂志,2020,6(5):279-284.
[26] 韩聪,赵耀东,朱玲,等.基于椎间盘退变生物力学探讨腰椎间盘突出症发病机制[J].中医临床研究,2020,12(1):47-50.

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备注/Memo

备注/Memo:
基金项目:四川省中医药管理局科学技术研究专项课题(2021MS430)
更新日期/Last Update: 2024-03-08