[1]戴羽,梁嘉欣,程韶峰,等.消肿定痛合剂治疗气滞血瘀型腰椎间盘突出症单侧双通道脊柱内镜术后临床研究[J].陕西中医,2026,(2):196-201.[doi:DOI:10.3969/j.issn.1000-7369.2026.02.009]
　DAI Yu,LIANG Jiaxin,CHENG Shaofeng,et al.Clinical study on treatment of unilateral double-channel spinal endoscopy for lumbar intervertebral disc herniation of Qi stagnation and blood stasis type with Xiaozhong Dingtong mixture[J].,2026,(2):196-201.[doi:DOI:10.3969/j.issn.1000-7369.2026.02.009]
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消肿定痛合剂治疗气滞血瘀型腰椎间盘突出症单侧双通道脊柱内镜术后临床研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2026年2期
页码:
196-201
栏目:
临床研究
出版日期:
2026-02-05

文章信息/Info

Title:
Clinical study on treatment of unilateral double-channel spinal endoscopy for lumbar intervertebral disc herniation of Qi stagnation and blood stasis type with Xiaozhong Dingtong mixture
作者:
戴羽1; 梁嘉欣1; 程韶峰1; 唐望2; 张宏艺2; 罗东斌2; 冯永辉2; 刘栋华2
（1.广州中医药大学，广东 广州 510006；2.广州市中西医结合医院，广东 广州 510800）
Author(s):
DAI Yu1; LIANG Jiaxin1; CHENG Shaofeng1; TANG Wang2; ZHANG Hongyi2; LUO Dongbin2; FENG Yonghui2; LIU Donghua2
(1.Guangzhou University of Chinese Medicine，Guangzhou 510006，China;2.Guangzhou Hospital of Integrated Traditional and Western Medicine,Guangzhou 510800,China)
关键词:
腰椎间盘突出症; 消肿定痛合剂; 单侧双通道脊柱内镜技术; 椎旁肌肉; 多裂肌; 腰椎功能
Keywords:
Lumbar disc herniation; Xiaozhong Dingtong mixture; Unilateral biportal endoscopy; Paravertebral muscle; Multifidus muscle; Lumbar spine function
分类号:
R 274
DOI:
DOI:10.3969/j.issn.1000-7369.2026.02.009
文献标志码:
A
摘要:
目的：探析消肿定痛合剂对腰椎间盘突出症（LDH）患者单侧双通道脊柱内镜技术（UBE）术后椎旁肌肉影响及临床疗效观察。方法：将90例拟行UBE治疗的气滞血瘀型LDH患者随机分类为对照组和治疗组。对照组予消炎止痛、脱水消肿、营养神经等治疗，治疗组在对照组治疗基础上加用消肿定痛合剂治疗。通过评估疼痛视觉模拟（VAS）评分、Oswestry功能障碍指数（ODI）评分、日本骨科协会（JOA）评分来分析两组患者治疗前后疼痛程度及腰椎功能状态变化，并比较两组患者治疗前后椎旁肌肉（多裂肌、竖脊肌）的信号强度、横截面积、水肿面积占比的变化情况。结果：在术后各时间点（术后1周、1、3个月），两组患者的VAS和ODI评分均相较前一观察节点逐次下降（均P＜0.05），JOA评分相较前一观察节点逐次下降（P＜0.05），且治疗组在同一观察节点的评分改善程度均优于对照组（P＜0.05）。椎旁肌肉方面，术后手术侧多裂肌其信号强度与水肿面积均较术前明显升高（均P＜0.05），并且其信号强度、横截面积、水肿面积占比相较于非手术侧均升高（均P＜0.05）。治疗组术后手术侧多裂肌信号强度、水肿面积占比低于对照组（均P＜0.05）。竖脊肌变化方面，UBE手术对竖脊肌上述指标改变程度未见统计学意义（均P＞0.05）。结论：消肿定痛合剂治疗腰椎间盘突出症UBE术后气滞血瘀型患者疗效较好，可有效缓解术后疼痛，促进腰椎功能恢复，改善术后椎旁肌肉损伤程度。
Abstract:
Objective:To explore effect of Xiaozhong Dingtong mixture on paraspinal muscles and clinical efficacy in patients with lumbar disc herniation (LDH) after unilateral biportal endoscopic surgery (UBE).Methods:90 patients with LDH of Qi stagnation and blood stasis type scheduled for UBE were randomly divided into control group and treatment group.The control group were treated with anti-inflammatory and analgesic,dehydration and swelling reduction,and neurotrophic therapy,while the treatment group was treated with Xiaozhong Dingtong mixture on the basis of the control group.The changes in pain degree and lumbar function before and after treatment were analyzed by evaluating visual analogue scale(VAS) score,Oswestry disability index (ODI) score,and Japanese orthopaedic association (JOA) score.The changes in signal intensity,cross-sectional area,and edema area ratio of paraspinal muscles (multifidus muscle and erector spinae muscle) before and after treatment were compared between the two groups.Results:At each postoperative time point (1 week,1 month,and 3 months after surgery),the VAS and ODI scores of both groups decreased successively compared with the previous observation node (all P＜0.05),and the JOA score decreased successively compared with the previous observation node (P＜0.05).The improvement degree of the treatment group at the same observation node was better than that in the control group (P＜0.05).In terms of paraspinal muscles,signal intensity and edema area of the multifidus muscle on the surgical side were significantly increased compared with those before surgery (all P＜0.05),and signal intensity,cross-sectional area,and edema area ratio were higher than those on the non-surgical side (all P＜0.05).The signal intensity and edema area ratio of the multifidus muscle on the surgical side in the treatment group were lower than those in the control group (all P＜0.05).Regarding the erector spinae muscle,there was no statistically significant difference in the changes of the above indicators after UBE surgery (all P＞0.05).Conclusion:Xiaozhong Dingtong mixture has a good therapeutic effect on patients with LDH of Qi stagnation and blood stasis type after UBE,which can effectively relieve postoperative pain,promote the recovery of lumbar function,and improve the degree of paraspinal muscle injury after surgery.

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备注/Memo

备注/Memo:
广东省中医药局项目（20242071）； 广州市中医药临床核心技术建设项目（穗卫中医〔2022〕7号）；广州市花都区科技计划项目（25-HDWS-024）
更新日期/Last Update: 2026-02-09